IACUC: Animal Alternatives

The journal Alternatives to Animal Experimentation (ALTEX) publishes open access academic articles on the development and implementation of alternatives to the use of animals for scientific purposes and informs on international developments in this field.

The Animal-Free Safety Assessment Collaboration (AFSA), is a unique multi-sector partnership between non-profit, corporate, and philanthropic leaders working to advance acceptance and use of animal-free safety science as a gold standard across regulatory frameworks worldwide.

Directory of preprint servers to find articles that have yet to be peer-reviewed. They may include relevant information but should be used with caution.

The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) is a global resource for the development of replacement, reduction and refinement alternatives for research and testing.

A comprehensive repository of links to governmental agencies, databases, examples of institutional websites, training resources, and more.

ILAR evaluates and reports on scientific, technological, and ethical use of animals and related biological resources, and of non-animal alternatives in non-food settings, such as research, testing, education, and production of pharmaceuticals.

Collection of reporting guidelines for research studies that involve animals, maintained by Iowa State University. Includes reporting guidelines for randomized controlled trials, observational studies, and experiments, as well as topic-specific guidelines.

A series of tutorials to assist you to develop your skills in the administration of substances and applying best practice in aseptic surgical techniques in laboratory rodents.

The Animal Welfare Information Center (AWIC) is mandated by the Animal Welfare Act (AWA) to provide information for improved animal care and use in research, testing, and teaching.

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) coordinates U.S. federal government evaluation of new, revised, and alternative test methods.

The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) focuses on the development and evaluation of alternatives to animal use for chemical safety testing.

The Office of Laboratory Animal Welfare (OLAW) oversees the care and use of research animals in Public Health Service (PHS)-funded research.

The Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART) is an independent body which was established to provide a focus for consideration of the scientific, ethical, and social issues associated with the use of animals in research and teaching.

Training modules intended as resources to support the development and implementation of the core and noncore topics of institutional training programs for animal care committees and all other personnel who work with animals.

The NC3Rs is a UK-based scientific organisation dedicated to replacing, refining, and reducing the use of animals in research and testing.

EURL ECVAM is an integral part of the Joint Research Centre (JRC) and includes a number of duties to advance the Replacement, Reduction and Refinement (the Three Rs) of animal procedures.

The Fund for the Replacement of Animals in Medical Education (FRAME) advocates the 3Rs approach to animal experimentation through the development, validation and acceptance of replacement alternative methods.

Training in how to monitor welfare in laboratory animals, identify endpoints, and define responsibilities. Part of the 3Rs Database Programme from the Centre Utrecht Life Sciences (ULS).

Collaborative multi-language resource for high quality, fully humane education and training in medicine, veterinary medicine, and biological science.

The Interspecies Database helps researchers to make an optimal choice of species and strain of the animal model, which is essential for efficient extrapolation of animal data to humans or other animals.

Norway’s national consensus platform and competence centre for ”the three Rs” (Replacement, Reduction and Refinement) in animal research. Includes 3R Guide (a global collection of information on databases, guidelines, information centres, journals and discussion forums) NORINA (alternatives and supplements to the use of animals in education and training) and TextBase (literature within laboratory animal science and related fields).