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Michigan State University

Evidence Based Medicine Guide: Studies

Information about and resources for evidence based medicine


Original single studies.  Can be preappraised or nonappraised.

Preappraised vs. Nonappraised

Preappraised sources have gone through a rigorous filtering process to assess their quality and currency.  Nonappraised sources may also include evidence based material, but remember that they may be outdated or of lower quality.

Available at MSU - Nonappraised Resources

Preappraised sources of studies include many of the resources that syntheses are found in.  The following are nonappraised resources available at MSU.  They make use of special filters to limit search results to evidence based results.

Other Sources of Studies - Federated Searches

Federated searches sort evidence across a range of databases and are ideal for those who don't know which database is best suited to answer their clinical question.  The quality of search results depends on the sources, and many do not offer critical appraisals of the evidence.
  • TRIP (Turning Research Into Practice) Database - Simultaneously searches evidence-based sources of systematic reviews, practice guidelines, and crtically-appraised topics and articles - including many of the resources found elsewhere in this guide.  Also searches PubMed MEDLINE's Clinical Queries, medical image databases, e-textbooks, and patient information leaflets.

Librarians - Medicine

Michigan State University